In order for the medicine to be effective and safe, patients should inform their doctor about all the medicines they are using, including prescription drugs, over-the-counter drugs and functional foods.įor more information or register for an appointment HERE.ĭownload MyVinmec app to make appointments faster and to manage your bookings easily. Administration with Methotrexate increases the toxicity of Methotrexate. Concomitant administration of ticlopidine increases the risk of bleeding. Combined with lithium increases serum lithium concentration and toxicity. Some of the signs of an overdose include: 5 Trouble breathing or inability to breathe. Benzodiazepine overdose symptoms may differ from person to person and depend on a variety of factors. Used with Glucocorticoids, Aspirin increases the risk of damage to the gastrointestinal tract. A benzodiazepine overdose can occur when a person takes more than their recommended dose or combines the sedative with another substance, such as alcohol. Concomitant use with quinolone antibiotics will cause side effects on the central nervous system, leading to convulsions. Concomitant use with anticonvulsants such as Carbamazepine, Barbitura, Phenytoi, anti-tuberculosis drugs will increase the risk of hepatotoxicity.
Use in combination with Probenecid will reduce the elimination of paracetamol. When using the drug, patients who drink alcohol will increase the risk of liver toxicity.
When using Zengesic with the following drugs, there may be some interactions that affect the effectiveness of the drug or increase unwanted side effects such as: Anticoagulants of the Coumarin, Heparin, Indandion group: Causes mild reactions that increase the anticoagulant effect, even if there is a risk of major bleeding.
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